What stain can differentiate myeloid cells except basophils?

Prepare for the Histopathologic Techniques Test. Utilize flashcards and multiple-choice questions with detailed explanations. Ace your exam with confidence!

Wright-Giemsa stain is commonly used in histopathology to differentiate various types of blood cells, including myeloid cells. It works by allowing for the visualization of cellular components due to its ability to stain different types of cells in varying intensities based on their cytoplasmic and nuclear characteristics.

In the context of myeloid cells, Wright-Giemsa stain enables the identification of granulocytes such as neutrophils and eosinophils by highlighting their distinct granules within the cytoplasm, while basophils, which have particularly strong granules, might be less distinct. This staining technique is particularly advantageous because it stains the blood cells well and provides morphological details that help distinguish myeloid cells from lymphoid cells.

The other stains mentioned do not specifically target or differentiate myeloid cells in the way Wright-Giemsa does. Levaditi's stain is primarily used to identify spirochetes, Grocott's methenamine silver is useful for fungal organisms, and Luxol fast blue with PAS is primarily used to stain myelin and polysaccharides, respectively. Therefore, Wright-Giemsa is uniquely suited for identifying myeloid cells, making it the correct choice.

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